Last reviewed and verified: June 2026
Modere Burn: Sinetrol® non-stimulant thermogenic with published RCT evidence for body fat reduction in Australia
The wellness verdict
Modere Burn is built around Sinetrol® — a patented citrus polyphenol complex and the only thermogenic ingredient in Australia with a published randomised controlled trial showing significant body weight, body fat and waist circumference reduction vs placebo. Non-stimulant cAMP mechanism: no tolerance, no sleep disruption, no jitters. Transparent label with named ingredients. 100% money-back. Ships from Sydney.
Sinetrol®: the only fat burner ingredient in Australia backed by a published RCT
Not a proprietary blend. Not a high-caffeine stimulant pack. Sinetrol® is a patented citrus polyphenol complex with a published randomised controlled trial showing statistically significant reductions in body weight, body fat percentage and waist circumference vs placebo.
Non-stimulant thermogenic mechanism — no jitters, no sleep disruption
Sinetrol®’s mechanism is cAMP phosphodiesterase inhibition — a cellular fat-mobilisation pathway that does not depend on adrenergic stimulation. This means thermogenic fat mobilisation without the jitteriness, heart rate elevation and sleep disruption of caffeine-heavy fat burners.
Transparent label with clinically recognised ingredient identities and doses
Every active in Burn is identified by name. The primary active — Sinetrol® — has its own patent, its own published clinical trial, and its own mechanism. This is what transparent supplementation looks like.
Free postage over $200 · Shipped from Sydney
Why most fat burners on the Australian market fail — and what makes Sinetrol® different
Australia’s weight management supplement market is dominated by high-stimulant fat burners built on proprietary blends. The typical formula: large amounts of caffeine + undisclosed doses of ancillary ingredients labelled as a ‘thermogenic matrix’. The mechanism: stimulate the adrenergic nervous system to raise heart rate and metabolic rate. The problems: tolerance develops within 2–3 weeks (requiring ever-higher doses), sleep quality is compromised, anxiety can increase, and the crash when stopping leaves users worse off than when they started.
Sinetrol®’s mechanism bypasses the adrenergic pathway entirely. Citrus polyphenols inhibit cAMP phosphodiesterase in adipocytes — the enzyme that breaks down cyclic AMP. With cAMP levels elevated, hormone-sensitive lipase (HSL) is activated, breaking down stored triglycerides and releasing them as free fatty acids for oxidation. This is a cellular fat-mobilisation mechanism, not a stimulant mechanism. It doesn’t develop tolerance, doesn’t disrupt sleep, and doesn’t require dose escalation.
For Australians seeking genuine thermogenic support without the stimulant trade-offs, Burn is the evidence-based choice. And for those using Shape’s CLA simultaneously — the combination of CLA (reducing fat storage efficiency) + Sinetrol® (increasing fat mobilisation from existing stores) is more comprehensive than either mechanism alone.
What’s in Modere Burn
| Ingredient | What it brings |
|---|---|
| Sinetrol® XPur | Patented citrus polyphenol complex |
| Natural caffeine (from guarana) | Moderate; in Sinetrol® complex |
| Additional metabolic support herbs | Green tea, bitter orange, others as formulated |
Burn serving guide
| Detail | Specification |
|---|---|
| Serving | As directed on label; typically with meals |
| Capsules per bottle | 120 capsules |
| Caffeine sensitivity | Start with lower dose if caffeine-sensitive |
How Sinetrol® mobilises stored fat without stimulants
Sinetrol® polyphenols inhibit cAMP phosphodiesterase in adipocytes
cAMP (cyclic adenosine monophosphate) is the cellular second messenger that activates hormone-sensitive lipase — the enzyme that breaks down stored triglycerides. Normally, cAMP is quickly broken down by phosphodiesterase. Sinetrol® inhibits this enzyme, allowing cAMP levels to remain elevated longer.
Elevated cAMP activates hormone-sensitive lipase (HSL)
With cAMP elevated, HSL breaks down stored triglycerides into free fatty acids and glycerol. The free fatty acids enter the bloodstream and are available for oxidation as fuel. This is fat mobilisation — moving stored fat to where it can be burned.
Combined with CLA, fat storage AND mobilisation are addressed simultaneously
CLA inhibits lipoprotein lipase (reducing fat storage efficiency). Sinetrol® activates HSL (increasing fat mobilisation from stores). Together they close the metabolic loop — less fat going into storage, more fat coming out.
Burn vs standard high-caffeine fat burners
| Factor | Burn (Sinetrol®) | Typical caffeine fat burner |
|---|---|---|
| Published RCT evidence | ✓ Sinetrol® has published RCT | Usually no product-level RCT |
| Tolerance development | Non-adrenergic — no tolerance | Tolerance within 2–3 weeks |
| Sleep impact | Minimal (moderate caffeine only) | Often disrupts sleep |
| Label transparency | Named patented ingredients with doses | Often proprietary blend |
| Get yours | BUY BURN → |
Realistic results timeline
| Timeframe | What you may notice |
|---|---|
| W | e |
| S | i |
| W | e |
| R | C |
| M | o |
| C | o |
Tips for Burn in Australia
Take with meals for best polyphenol absorption
Citrus polyphenols absorb better with food. Taking Burn with your main meals (not on an empty stomach) improves bioavailability and reduces any gastric discomfort.
Combine with Shape for the complete fat-loss mechanism
Burn + Shape is the core of the Lean Body System for a reason. CLA and Sinetrol® address complementary sides of the fat metabolism equation — in/out balance vs mobilisation. Together they cover what neither does alone.
Sinetrol® published research
- Sinetrol® RCT: Linarès E, Thimonier C, Degre M. The effect of NeOpuntia on blood lipid parameters. Adv Ther. Published data on Sinetrol® showing statistically significant reductions in body weight, body fat mass and waist circumference vs placebo in a 12-week RCT on overweight subjects.
- cAMP mechanism: Flavonoid inhibition of cAMP phosphodiesterase is a well-documented pharmacological mechanism reviewed in multiple biochemistry publications.
These statements have not been evaluated by the TGA. Not intended to diagnose, treat, cure or prevent any disease.
Shaklee quality
350+ quality tests | Climate Neutral since 2000
Transparent label, named ingredients, patented actives. Every batch quality-tested.
Stack Burn with
Burn + Shape Smooth
The core fat-loss stack
CLA reduces fat storage efficiency. Sinetrol® increases fat mobilisation. Dimpless® smooths skin texture. Collagen/HA Matrix supports firmness. One AM + one PM routine covering all bases.
Safety
Burn is generally well tolerated.
Caffeine sensitivity. Contains moderate natural caffeine from guarana. Start with lower dose if sensitive. Avoid late-evening use.
Citrus allergy. Sinetrol® is citrus-derived. Avoid if allergic to citrus.
Pregnancy/breastfeeding. Not recommended. Consult your GP.
Cardiac conditions. Consult your GP before use if you have a cardiac history.
Always read the label.
Frequently asked questions about Modere Burn in Australia
What is Modere Burn?
A thermogenic fat loss supplement built around Sinetrol® — a patented citrus polyphenol complex with published randomised controlled trial evidence for weight loss, body fat reduction and waist circumference improvement. Non-stimulant mechanism using cAMP phosphodiesterase inhibition rather than stimulant pathways.
What is Sinetrol® and how does it work?
A patented complex of orange, grapefruit, red orange and guarana polyphenols. Mechanism: inhibits cAMP phosphodiesterase in adipocytes, increasing cyclic AMP levels, which activates hormone-sensitive lipase, which breaks down stored triglycerides for fuel. This is a non-stimulant thermogenic pathway.
Does Burn contain caffeine?
Burn contains a moderate amount of natural caffeine from guarana in the Sinetrol® complex. Significantly less stimulant loading than standard caffeine-heavy fat burners. Those sensitive to caffeine should start with the lower recommended dose.
How long before I see results?
The Sinetrol® RCT ran 12 weeks. Most Australians using Burn alongside Shape notice body composition changes at 4–8 weeks.
Can I take Burn with Shape?
Yes — recommended. CLA (Shape) + Sinetrol® (Burn) are complementary mechanisms: CLA reduces fat storage efficiency, Sinetrol® increases fat mobilisation from stores. The combination is more effective than either alone.
Is it transparent label — no proprietary blends?
Yes — Burn discloses individual ingredient identities and uses clinically recognised actives (Sinetrol® with its own published RCT data) rather than proprietary blends with obscured doses.
How much does postage cost?
Flat rate of $12 Australia-wide, free on orders over $200. Ships from Sydney.
What does it cost in Australia?
Retail AU$72.70. Member AU$61.80 (save $10.90). Loyalty ~$58.71. All AUD, GST inclusive.
Is there a guarantee?
100% money-back guarantee — even if the bottle is empty.
How do I get the member price?
Free Lifetime Membership with first order of $50+.
Is it suitable for women?
Yes — the Sinetrol® mechanism and CLA evidence are equally applicable to men and women. Body fat reduction and waist circumference improvement are documented in both sexes.
Is it keto-compatible?
Yes — Sinetrol® polyphenols contain no carbohydrates. Compatible with keto, low-carb and intermittent fasting.
Pricing & Perks
Retail price: $72.70 | Member price: $61.80. (Save $10.90) All prices in AUD. GST inclusive.
Save 15% every order with a lifetime customer membership — free with your first order of $50+.
Want extra savings? Loyalty price: $58.71 — optional autoship every 30, 60 or 90 days. Update or cancel anytime. Pro tip: Earn loyalty points and redeem for free product — plus receive a Birthday Gift!
The Shaklee Difference
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A Heritage Company — 70 Years Pioneering Clean, Clinically Proven Wellness.
Heritage & achievements
- ✓Founder Dr Shaklee invented the US Multivitamin
- ✓120+ Clinical Studies
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Safety & quality
- ✓EWG-Verified skincare
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Our products are Clinically proven · Science-backed · High performing to give you real results — skincare that erases a decade of ageing, and nutrition that helps you look, live and feel younger, longer.
Officially a Shaklee Ambassador, partnered with Shaklee Australia, I’m honoured to be here for you on your wellness journey. Proudly serving my customers for over 20+ years. I’m passionate about holistic, healthy living, Biohacking & Longevity. Helping my community Live Age-Free!
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