Last reviewed and verified: June 2026
Modere Stress Health: Lactium, St John’s Wort and B vitamins for stress and nervous tension, Australia
The wellness verdict
Modere Stress Health is a 90-tablet formula combining Lactium (alpha casozepine 50mg — GABA-stimulating milk peptide), St John’s Wort dry extract 300mg, and vitamins B6, B12 and folic acid. 1 tablet 3 times daily with meals. Important: check for St John’s Wort drug interactions before starting. Back at Shaklee Australia.
Lactium (alpha casozepine 50mg) stimulates GABA — the same mechanism as pharmaceutical anxiolytics, from milk peptide
A 90-tablet formula from the AU official label: alpha casozepine (Lactium 50mg per tablet) from milk protein stimulates GABA receptor activity to inhibit anxiety and the stress response; St John’s Wort dry extract (300mg) for traditional nervous tension support; vitamins B6, B12 and folic acid for neurotransmitter synthesis. 1 tablet 3 times daily with meals.
GABA is the brain’s primary calming neurotransmitter — Lactium stimulates it via food-derived peptide chemistry
GABA (gamma-amino butyric acid) reduces neuronal excitability — the physiological mechanism of anxiety reduction. Pharmaceutical benzodiazepines work by enhancing GABA activity. Lactium’s alpha casozepine peptide stimulates the same GABA receptors through a natural, food-derived milk protein pathway.
90 tablets — most ingredient-specific stress formula in the Modere range, back at Shaklee Australia
Combines mechanism (Lactium + St John’s Wort) with cofactors (B6, B12, folic acid). Check for St John’s Wort drug interactions before starting. 100% money-back guarantee.
Free postage over $200 · Shipped with care from Sydney
Why modern Australian stress is a physiological challenge, not just a mindset problem
Chronic psychological stress activates the HPA axis, driving elevated cortisol, reduced GABA activity, disturbed sleep and impaired serotonin signalling. These are measurable physiological changes. The nervous system’s response to sustained stress shows in hormone levels, brainwave patterns and neurotransmitter concentrations — it is not simply about perspective or coping skills.
The most effective nutritional approaches to stress address both the neurotransmitter systems involved and the cofactors those systems require. Lactium’s GABA-stimulating mechanism directly addresses the inhibitory deficit that underlies the hyper-aroused, anxious state. St John’s Wort adds traditional herbal nervous system support. The B vitamins ensure the neurotransmitter synthesis machinery is not limited by nutritional deficiency — a common scenario under sustained stress.
Active ingredients (AU official label)
| Ingredient | What it brings |
|---|---|
| Alpha casozepine (Lactium) 50mg per tablet | Bioactive peptide from casein (cow’s milk); stimulates GABA-A receptor activity, reducing neuronal excitability and promoting a calmer state; the AU label states it helps alleviate daily stress, nervous tension and mild anxiety |
| St John’s Wort (Hypericum perforatum) 300mg dry extract | From 1.8g dry flowering tops; traditional Western herbal medicine nerve tonic for mild anxiety and nervous tension; one of the most studied herbs in this category |
| Vitamins B6, B12 and folic acid | Essential cofactors for neurotransmitter synthesis (B6 for serotonin and GABA; B12/folate for methylation); addresses the nutritional dimension of stress-related symptoms |
How the three ingredients work together
Lactium stimulates GABA for direct nervous system calming
GABA is the brain’s primary inhibitory neurotransmitter. Alpha casozepine binds to GABA-A receptors to increase inhibitory tone, promoting a calmer neural state — the same receptor mechanism as pharmaceutical anxiolytics, via a natural milk-derived peptide.
St John’s Wort supports mood and nervous resilience
St John’s Wort modulates serotonin, dopamine and noradrenaline signalling, and reduces inflammatory markers that contribute to stress-driven mood changes. Traditional Western herbal medicine has relied on it for nervous system support for centuries.
B vitamins ensure neurotransmitter synthesis is not rate-limited
Without adequate B6, the conversion of 5-HTP to serotonin and glutamate to GABA is impaired. Without B12 and folate, the methylation cycle that recycles neurotransmitters falters. The B vitamin combination ensures the biochemical machinery behind both Lactium and St John’s Wort can function optimally.
What to expect and when
Weeks 2–4 (Lactium)
GABA receptor modulation by Lactium develops over 2–4 weeks. Improved sleep quality and reduced nervous tension are usually the first noticeable changes.
Weeks 4–8 (St John’s Wort)
Herbal nervous system support from St John’s Wort develops over 4–8 weeks of consistent use, consistent with clinical evidence for herbal interventions in mild anxiety.
Ongoing (B vitamins)
The B vitamin cofactors have immediate nutritional benefit for anyone with borderline B12, B6 or folate status — common in people under sustained stress.
Tips for Stress Health
Take with meals — 1 tablet 3 times daily as directed
Splitting the dose across the day maintains consistent circulating levels rather than a single peak-and-trough profile.
Allow 4–8 weeks for the full cumulative effect
Neither Lactium nor St John’s Wort is an immediate anxiolytic. The benefits build over weeks of consistent daily use.
Check for drug interactions before starting — this is critical
St John’s Wort induces CYP450 liver enzymes and significantly reduces blood levels of oral contraceptives, antiretrovirals, warfarin, cyclosporin and many other medications. If you take any regular medication, check with your GP or pharmacist first.
Safety
Contains Lactium (milk protein peptide) and St John’s Wort. Read all warnings carefully.
St John’s Wort drug interactions (CRITICAL). St John’s Wort induces CYP3A4 enzymes, significantly reducing blood levels of oral contraceptives, antiretrovirals, warfarin, cyclosporin and others. Check with your GP or pharmacist if you take any regular medications.
Milk protein allergy. Lactium is derived from cow’s milk casein. Not suitable if you have a milk protein allergy.
Antidepressants / SSRIs / MAOIs. Do not take with antidepressants, SSRIs or MAOIs. Risk of serotonin syndrome.
Pregnancy. St John’s Wort is not recommended during pregnancy. Consult your GP.
Always read the label. If symptoms persist, consult your healthcare professional.
FAQ — Modere Stress Health Australia
What is Modere Stress Health?
A 90-tablet formula combining Lactium (alpha casozepine 50mg, from milk protein) with St John’s Wort dry extract (300mg per tablet, from 1.8g dry herb) and vitamins B6, B12 and folic acid. Supports the nervous system during stress, calms nerves and reduces mild anxiety and nervous tension. 1 tablet 3 times daily with meals. AU official label ingredients.
What is Lactium (alpha casozepine)?
Alpha casozepine is a bioactive peptide derived from casein (cow’s milk protein), marketed as Lactium. It stimulates GABA (gamma-amino butyric acid) receptor activity in the brain. GABA is the primary inhibitory neurotransmitter that reduces neuronal excitability. The AU label specifically states Lactium helps alleviate the effects of daily stress, nervous tension and mild anxiety via this GABA-stimulating mechanism.
What does St John’s Wort do?
St John’s Wort (Hypericum perforatum) is used traditionally in Western herbal medicine to reduce mild anxiety and nervous tension. The AU formula uses a standardised dry extract at 300mg per tablet (from 1.8g dry herb). It is one of the most extensively studied herbs for nervous system support.
Why are B vitamins in a stress formula?
B6, B12 and folic acid are essential cofactors for neurotransmitter synthesis. B6 is required for serotonin and GABA production; B12 and folate are required for the methylation cycle that maintains neurotransmitter balance. Deficiency in any of these is associated with increased anxiety symptoms.
Is there an important drug interaction warning?
Yes. St John’s Wort is a well-known inducer of CYP3A4 liver enzymes and significantly reduces blood levels of many medications including oral contraceptives, antiretrovirals, warfarin, and cyclosporin. Always check with your GP or pharmacist if you take any regular medications before starting this product.
Postage?
Flat rate $12 Australia-wide, free over $200.
Cost?
Retail $90.95, member $77.30 AUD. GST inclusive.
Guarantee?
100% money-back guarantee.
Pricing & Perks
Retail: $90.95 | Member: $77.30 (save $13.65) AUD, GST inclusive.
Save 15% every order with a Shaklee membership. Postage is a flat rate of $12 Australia-wide, free over $200.
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